No quarter-final place for David Goffin
The fourth seed Wawrinka is bidding to emulate his compatriot Roger Federer and become only the fifth man in the professional era to win the French Open and Wimbledon back-to-back.
Wawrinka is yet to drop a set so far, although Goffin forced the 30-year-old to produce some of his best tennis.
Sixteenth seed Belgian Goffin, in the fourth round for the first time, had a point to level the match at one set apiece and was a break ahead in the third set before Wawrinka reeled off a succession of brilliant backhands to close out victory.
Leading 5-4 on the Goffin serve Wawrinka dug out a glorious backhand down the line to move 0-30 ahead and, when Goffin double-faulted to offer up matchpoints, Wawrinka ended the contest with a similarly spectacular forehand.